Saturday, May 8, 2010

Not Telling, Encouraging Stats, Rooting for Pie

Ahh, it's a lazy Saturday morning! I love it. Thought I'd do an update on a couple of things:

I made it through the meeting with the boss yesterday without any inquiries about the outcome of the FET. I was ready, thanks to comments on my previous post, but didn't even need to evade any questions. I had a stroke of luck, actually, and was able to preempt any inquiries by bringing it up first. My boss told me that one our colleagues, a man with a big personality who's always making people laugh, is leaving the organization. This is a big loss for us. I was saying things like, "Oh no!!!! This is terrible!" Well, this guy always conducts a "baby pool" among all staff whenever a woman is expecting. (I have never participated but basically, people bet on when the baby will be born and the person who's closest wins the pot of money.) In the midst of my very genuine "oh no" reaction, something flashed through my mind. My opportunity! So I said, "WHO is going to do my baby pool when I have a baby someday?!" Somehow I knew that my boss, who I know pretty well, would not ask me about the FET after I said this. She just said, "I don't know. I guess someone else will have to do it." And that was it! Ha! I am probably safe until my next meeting with her, which isn't until after the six week ultrasound. Whew!

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I left work a little bit early yesterday because I worked so late Thursday night. I went home to rest a bit and found myself feeling anxious about making it nearly 2 more weeks to the six week ultrasound. This is a whole 'nother 2ww! I pulled up an old email from CCRM's genetic counselor in which she provided me with a statistical summary for people who've had comprehensive chromosone screening (CCS). Here it is, verbatim:

2007-2009 Blastocyst-CCS General Update
N = 154 transfers
Average maternal age = 37.5
Average number of embryos transferred = 1.87
97% survival post vitrification
~61 % implantation rate
~74% clinical pregnancy rate (6 week ultrasound)
~71% ongoing clinical pregnancy

13% of patients who undergo blast biopsy had all aneuploid* embryos. This means 87% of the patients had at least one normal embryo available to transfer. Of the 154 woman who have had transfers (this does not include the patients whose embryos were all abnormal) of euploid** blastocyst embryos, ~110 have delivered a healthy baby (or babies). I calculated this number by taking 71% of 154 (see stats above).

* “aneuploid” means chromosomally abnormal
** “euploid” means chromosomally normal

I wanted to know where I am in those statistics now, so I called her -- and luck was on my side, I caught her! -- to ask a few clarifying questions. I was thinking the 61% implantation rate was a typo but she said it is not, because it is a calculation of implantation of each embryo transferred.

I asked about rates of miscarriage and she said they don't track them at every step of the way. BUT what she did say was very good news -- the miscarriage rate for women in this study after they had positive betas was just 4 to 5 percent!! This is exactly the kind of reassuring information I was seeking. I could, of course, be in that 4-5 percent, but my mind is at peace with those odds.

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Last but not least, today I am thinking a lot about Pie, whose beta is tomorrow -- on Mother's Day! That's just wrong. And to top it off, her husband is out of town until tomorrow. If you have a minute today, say a prayer, send some sticky vibes, or visit Pie's blog and leave an encouraging comment. Pie, I am rooting for you!

6 comments:

  1. Awwww, thanks Susie. I'm doing ok, and your positive thoughts help me. Fingers crossed I'm in the 61%!!

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  2. I am rooting for both of you!!!

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  3. I've been reading your blog from a link from another blog :) Congratulations on your pregnancy!
    I am hoping to do a cycle at CCRM with CGH. The stats are so encouraging!! Thanks for sharing.
    I look forward to following your blog and hope I can have such success as you!!

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  4. Those are encouraging stats and catching the counselor on the phone to hear the super low precentage is even better.

    Hang in there, I know its another hoop, another 2ww, but it will be here very soon and then you can look foward to more and more ultrasounds!!

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  5. That was so SMART pre-empting any questions! Genius! Hope your spirits are up.

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  6. Glad the meeting went so well!

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